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- 產(chǎn)品名稱： αvβ1 integrin-IN-1
- 產(chǎn)品貨號(hào)： CST13473
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購： 800
- 數(shù)量：
庫存： 5
- 規(guī)格： 10mg
- 產(chǎn)品信息
- 如何訂購
產(chǎn)品描述
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.
靶點(diǎn)活性
αvβ1 integrin:0.63 nM , αvβ1 integrin:0.63 nM
體外活性
In a murine model of liver and lung fibrosis, the administration of αvβ1 integrin-IN-1 leads to a significant reduction in the expression of fibrotic markers.[1]
分子量
558.65
分子式
C26H34N6O6Sicon
化學(xué)結(jié)構(gòu)
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CAS No
1689540-62-2
存儲(chǔ)
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 5.59 mg/mL (10 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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參考文獻(xiàn)
1. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett. 2016 ; 7(10):902-907.
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Note
For research use only.
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