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- 產(chǎn)品名稱： Anti RheB Mouse Monoclonal Antibody
- 產(chǎn)品貨號： CS26015
- 貨期： 現(xiàn)貨
- 價格與訂購： 2800
- 數(shù)量：
庫存： 100
- 規(guī)格： 100μl 200μl
- 產(chǎn)品信息
- 如何訂購
Catalog Number
CS26015
Gene Symbol
RHEB
Description
Anti RheB Mouse Monoclonal Antibody
Background
RheB (Ras Homolog Enriched in Brain) is an evolutionarily conserved member of the Ras-family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, RheB is widely expressed in other tissues and may be induced by growth factor stimulation. RheB has an important role in regulating the insulin/TOR signaling pathway. The mammalian target of rapamycin, mTOR, is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with translation and cell growth. The tuberin/hamartin (TSC2/TSC1) complex inhibits mTOR activity indirectly by inhibiting RheB via tuberin's GAP activity.
Immunogen
Recombinant full length protein of RheB.
Applications
ELISA, WB, IHC
Recommended Dilutions
ELISA: 1:100-1:5000
WB: 1:100-1:2000
IHC: 1:50-1:100
Concentration
1 mg/ml
Host
mouse
Format
Liquid
Clonality
Monoclonal
Isotype
IgG
Purity
Purified from ascites
Preservative
no
Constituents
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity
RheB antibody recognizes RheB proteins of vertebrates.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles
Western blot
Western blot analysis of RheB proteins. HEK-293 whole-cell lysate was used for Western blot.
Note
For research use only .
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