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- 產(chǎn)品名稱： Recombinant Human MAEA protein
- 產(chǎn)品貨號： CSP01415
- 貨期： 現(xiàn)貨
- 價格與訂購： 1800
- 數(shù)量：
庫存： 100
- 規(guī)格： 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述（Summary）
英文全稱
Recombinant Human MAEA protein
純度（Purity）
>90% as determined by SDS-PAGE
內(nèi)毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白構(gòu)建（Construction）
A DNA sequence encoding the human MAEA (Cys136-Pro379) was fused with His tag
Accession #
Q7L5Y9
表達宿主（Host）
E.coli
種屬（Species）
Homo sapiens (Human)
預測分子量（Predicted Molecular Mass）
28.9 kDa
制劑（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
運輸方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩(wěn)定性&儲存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介紹
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation . The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1. Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages. Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages . May contribute to nuclear architecture and cells division events.
分子別名（Alternative Names）
Cell proliferation-inducing gene 5 protein
Erythroblast macrophage protein
Human lung cancer oncogene 10 protein
Short name:
HLC-10
Macrophage erythroblast attacher
P44EMLP
Erythroblast macrophage protein
Human lung cancer oncogene 10 protein
Short name:
HLC-10
Macrophage erythroblast attacher
P44EMLP
Note
For research use only .
地 址：
產(chǎn)品銷售：
E - mail ：
郵 編：
Amily
