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  • 產(chǎn)品名稱: Recombinant Human MCM2 protein
  • 產(chǎn)品貨號: CSP00447
  • 貨期: 現(xiàn)貨
  • 價格與訂購: 1800
  • 數(shù)量:
    庫存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購
    概述(Summary)
    英文全稱
    Recombinant Human MCM2 protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構(gòu)建(Construction)
    A DNA sequence encoding the human MCM2 (Phe657-Phe904) was fused with His tag
    Accession #
    P49736
    表達(dá)宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預(yù)測分子量(Predicted Molecular Mass)
    29.2 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis.
    分子別名(Alternative Names)
    DNA replication licensing factor MCM2,Minichromosome maintenance protein 2 homolog,Nuclear protein BM28.
    Note
    For research use only .
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