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- 產(chǎn)品名稱： Research Grade Plamotamab (帕拉莫妥單抗 )
- 產(chǎn)品貨號(hào)： CSD00605
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購： 2480
- 數(shù)量：
庫存： 100
- 規(guī)格： 100μg
- 產(chǎn)品信息
- 如何訂購
貨號(hào)（Catalog No.）
CSD00605
通用名INN
Plamotamab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Plamotamab (XmAb13676) is a tumor-targeted antibody that contains both a CD20 binding domain and a cytotoxic T-cell binding domain (CD3).An XmAb Bispecific Fc domain serves as the scaffold for these two antigen binding domains and confers long circulating half-life,stability and ease of manufacture on plamotamab.CD20 is highly expressed on B-cell tumor cells, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL) cells.Engagement of CD3 by plamotamab activates T cells for highly potent and targeted killing of CD20-expressing tumor cells. The structural stability and modularity enabled by the XmAb Bispecific Fc domain allowed the tuning of plamotamab’s potency to balance anti-tumor activity with the reduction of immune toxicity that can result from T-cell activation.
別名(Alternative names)
XmAb-13676
靶點(diǎn);物種(Specificity target name;species)
CD3E/MS4A1[Homo sapiens]
種類(Species)
Chimeric,Humanized
受體鑒定(Receptor identification)
IgG1-kappa / scFv-h-CH2-CH3
CAS
2138442-31-4
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .
地 址：
產(chǎn)品銷售：
E - mail ：
郵 編：
Amily
