Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only FDA approved treatment specifically developed to prevent migraine by blocking the CGRP receptor, which is believed to play a critical role in migraine .
別名(Alternative names)
AMG 334,erenumab-aooe
靶點;物種(Specificity target name;species)
CALCRL/CGRP-R[Homo sapiens]
種類(Species)
Homo sapiens
受體鑒定(Receptor identification)
IgG2-lambda
分子量(MV)
150000.00 Da
CAS
1582205-90-0
存儲條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.