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- 產(chǎn)品名稱： Compound 401
- 產(chǎn)品貨號： CS3586
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購： 600
- 數(shù)量：
庫存： 100
- 規(guī)格： 2mg 5mg 10mg
- 產(chǎn)品信息
- 如何訂購
產(chǎn)品描述
Compound 401 is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.
靶點(diǎn)活性
DNA-PK
體外活性
Compound 401 shows activity against mTOR (IC50 = 5.3 μM) but not p110α/p85α PI3K (IC50 > 100 μM). Treatment of cells with Compound 401 blocks the phosphorylation of sites modified by mTOR-Raptor and mTOR-Rictor complexes (ribosomal protein S6 kinase 1 Thr389 and Akt Ser473, respectively).
別名
2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
純度
99.76%
分子量
281.31
分子式
C16N15H3O2
CAS No
168425-64-7
存儲
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
溶解度
DMSO: 6 mg/mL
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Note
For research use only .
地 址：
產(chǎn)品銷售：
E - mail ：
郵 編：
Amily
