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- 產(chǎn)品名稱： Recombinant Human CD244 protein
- 產(chǎn)品貨號： CSP01683
- 貨期： 現(xiàn)貨
- 價格與訂購： 1800
- 數(shù)量：
庫存： 100
- 規(guī)格： 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述（Summary）
英文全稱
Recombinant Human CD244 protein
純度（Purity）
>90% as determined by SDS-PAGE
內(nèi)毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白構(gòu)建（Construction）
A DNA sequence encoding the human CD244 (Cys22-Pro229) was fused with His tag
Accession #
Q9BZW8
表達宿主（Host）
E.coli
種屬（Species）
Homo sapiens (Human)
預測分子量（Predicted Molecular Mass）
23.68 kDa
制劑（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
運輸方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩(wěn)定性&儲存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介紹
Natural killer cell receptor 2B4 is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family.2B4 interacts with CD48, while other SLAM family proteins interact homophilically. Three additional splice variants of human 2B4 have deletions of the short region between the Ig-like domains, the second Ig-like domain, or a portion of the cytoplasmic tail.2B4 is expressed on all NK cells, γδ T cells, monocytes, some CD4+ and CD8+ T cells, and some dendritic cells. CD48 mediates 2B4+ cell interactions with nearly all hematopoietic cell types, including cells of the same type. 2B4/CD48 signaling cooperates with other receptor systems to either promote or inhibit NK and CD8+ T cell activation. The inhibitory activities are distinct from those of MHC I restricted inhibitory NK cell receptors. Ligation of 2B4 with antibodies or CD48 constructs can either directly trigger inhibitory signaling or disrupt an inhibitory interaction, leading to cellular activation. The inhibitory effect is associated with the long form of 2B4, while the activation is associated with the short form. 2B4 can also induce signaling through CD48.
分子別名（Alternative Names）
Natural killer cell receptor 2B4,NK cell activation-inducing ligand,Short name:NAIL,NK cell type I receptor protein 2B4,Short name:NKR2B4,Short name:h2B4,SLAM family member 4,Short name:SLAMF4,Signaling lymphocytic activation molecule 4,CD_antigen: CD244.
Note
For research use only .
地 址：
產(chǎn)品銷售：
E - mail ：
郵 編：
Amily
